This summer, the Department of Mathematics is running an online Special Colloquium Lecture Series on mathematical analysis and applications in allied fields. This lecture series is presented in conjunction with UTC’s NSF-funded Math REU Site. The fourth lecture will be given Friday, July 22nd by Dr. Wenrui Hao, Professor of Mathematics at Pennsylvania State University. I have included the details of Dr. Hao’s lecture below. Undergraduate and graduate students who are interested in Computational Biology and Mathematical Modeling are especially encouraged to attend.
Date: Friday, July 22, 2022
Time: 1:00 p.m.-2:00 p.m. (EDT)
Zoom link: https://tennessee.zoom.us/j/94590120710
Title: Data-driven modeling on Alzheimer’s disease
Abstract: Alzheimer’s disease (AD) affects more than 5 million people in the US. Recently, personalized treatment of AD provides a new way to manage AD patients’ treatment plans. Such treatment requires a new approach to analyze the growing electronic AD brain data. In this talk, we will introduce a mathematical modeling approach to describe the progression of AD clinical biomarkers and also incorporate patient data for personalized prediction and optimal treatment. More specifically, an AD personalized prediction is provided via validating the mathematical model on a multi-institutional dataset of AD biomarkers. Personalized therapeutic simulation studies for AD patients are performed via adding optimal controls to this model.